TOP AVANA (Generic Stendra+Dapoxetine)
Avanafil 50 mg + Dapoxetine 30 mg
| Quantity of Tablets | Price per Tablet | Total |
|---|---|---|
| 4 | 5.6 $ | 22.4 $ |
| 8 | 5.5 $ | 44 $ |
| 12 | 5.4 $ | 64.8 $ |
| 20 | 5.2 $ | 104 $ |
| 40 | 5 $ | 200 $ |
| Manufacturer | Sunrise Remedies |
| Active Ingredient | Avanafil + Dapoxetine |
| Dosage | 50 mg + 30 mg |
| Expiration Date | Until 2027 |
| How to Take | 1 hour before sex |
| Duration of Action | Up to 12 hours |
| Daily Dosage | 2 pills |
| Compatibility with Alcohol | Yes |
TOP AVANA is a modern combination drug designed to treat erectile dysfunction (ED) and premature ejaculation (PE) in men. Thanks to the combination of two active components, avanafil and dapoxetine, TOP AVANA provides a comprehensive approach to solving these delicate problems, returning men control over erection and duration of sexual intercourse.
What are TOP AVANA tablets?
TOP AVANA are tablets for oral administration containing a unique combination of two active substances: avanafil (50 mg) and dapoxetine (30 mg) .
- Avanafil is a potent and selective inhibitor of phosphodiesterase type 5 (PDE5). PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP) in the cavernous bodies of the penis. cGMP is responsible for relaxing the smooth muscles of blood vessels, which leads to increased blood flow and erection. By blocking PDE5, avanafil increases cGMP levels, promoting a persistent erection with sexual stimulation. Avanafil has a rapid onset of action and high selectivity for PDE5, which minimizes the risk of side effects.
- Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI). Serotonin is a neurotransmitter that plays an important role in the regulation of ejaculation. By inhibiting the reuptake of serotonin, dapoxetine increases its concentration in the synaptic cleft, which leads to delayed ejaculation and prolongation of sexual intercourse.
Thanks to the synergistic action of these two components, TOP AVANA effectively combats both problems simultaneously, providing a comprehensive solution for improving the quality of sexual life.
What is the composition of TOP AVANA?
Each TOP AVANA tablet contains:
- Avanafil (50 mg): active ingredient, PDE-5 inhibitor.
- Dapoxetine (30 mg): active ingredient, SIOS.
- Excipients:
- Lactose monohydrate: filler.
- Microcrystalline cellulose: filler and binder.
- Crosscarmellose sodium: disintegrant.
- Silicon dioxide colloidal anhydrous: anti-caking agent.
- Magnesium stearate: lubricant.
- Hypromellose (hydroxypropyl methylcellulose): film-forming agent.
- Titanium dioxide (E171): white pigment.
- Triacetin: plasticizer.
- Dyes: May be added for identification.
Who is the manufacturer of TOP AVANA and what is a generic?
TOP AVANA is manufactured by the Indian pharmaceutical company Sunrise Remedies Pvt. Ltd. , which is a renowned manufacturer of high quality generic drugs.
TOP AVANA is a generic , i.e. a drug containing the same active ingredients in the same doses as the original, but not patented, drugs. In this case, TOP AVANA combines the active ingredients of Stendra/Spedra (avanafil) and Priligy (dapoxetine). Generics undergo strict quality control and must prove their bioequivalence to original drugs. This means that they are absorbed by the body in the same way as original drugs and provide an identical therapeutic effect. Due to the absence of development and research costs, generics are usually much cheaper than original drugs.
Why take TOP AVANA?
TOP AVANA is intended for the treatment of men suffering from both erectile dysfunction (ED) and premature ejaculation (PE) .
- Erectile dysfunction (ED) is the inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse.
- Premature ejaculation (PE) is a condition in which ejaculation occurs earlier than desired by a man or his partner, with minimal sexual stimulation.
TOP AVANA, thanks to its combined action, helps to solve both problems, providing a stable erection and prolonged sexual intercourse.
How to take TOP AVANA?
The recommended dose of TOP AVANA is one tablet taken 30-60 minutes before expected sexual activity. The tablet should be swallowed whole with plenty of water. It is not recommended to take more than 1 tablet per day.
Important:
- TOP AVANA works only with sexual stimulation. The drug is not an aphrodisiac and does not automatically cause an erection.
- Avanafil, which is part of TOP AVANA, begins to act on average 15-30 minutes after administration.
- The effects of dapoxetine usually appear within 1-3 hours after administration.
- The duration of action of avanafil can reach 6 hours , and dapoxetine – up to 4-6 hours .
- Consuming alcohol and fatty foods may reduce the effectiveness and slow down the action of the drug.
What are the contraindications for TOP AVANA?
TOP AVANA has a number of contraindications associated with the presence of two active substances in its composition:
- Hypersensitivity to avanafil, dapoxetine or any other component of the drug.
- Concomitant administration of nitrates in any form (nitroglycerin, isosorbide mononitrate, isosorbide dinitrate, etc.).
- Concomitant use of nitric oxide donors (eg, amyl nitrite).
- Concomitant use of monoamine oxidase inhibitors (MAOIs) or use of TOP AVANA within 14 days of stopping treatment with MAOIs. Also, do not start taking MAOIs within 7 days of stopping TOP AVANA.
- Concomitant administration of thioridazine .
- Concomitant administration of strong CYP3A4 inhibitors (eg, ketoconazole, itraconazole, ritonavir).
- Severe cardiovascular diseases in which sexual activity is not recommended (unstable angina, severe heart failure).
- Recently suffered a myocardial infarction (last 90 days).
- Recently suffered a stroke (within the last 6 months).
- Hereditary degenerative diseases of the retina , such as retinitis pigmentosa.
- Loss of vision in one eye due to non-arteritic anterior ischemic optic neuropathy (NAINO).
- Moderate and severe hepatic impairment.
- Severe renal failure.
- Age up to 18 years and over 65 years.
- Female gender.
- Orthostatic hypotension has been diagnosed or suspected.
- Manic state or severe depression.
Does TOP AVANA have any side effects?
Like any medication, TOP AVANA can cause side effects. The most common side effects are related to the action of avanafil and dapoxetine and include:
- Headache.
- Nausea.
- Dizziness.
- Flushing of blood to the face.
- Nasal congestion.
- Dyspepsia (indigestion).
- Diarrhea.
- Fatigue.
- Insomnia.
- Dry mouth.
Less common side effects may include:
- Changes in vision.
- Tinnitus.
- Tachycardia (rapid heartbeat).
- Increase or decrease in blood pressure.
- Anxiety, excitement.
- Decreased libido.
- Back and muscle pain.
In rare cases the following are possible:
- Fainting.
- Orthostatic hypotension.
If serious side effects occur, especially those related to vision, hearing, cardiovascular system or mental state, you should stop taking the medicine immediately and consult a doctor.
Can TOP AVANA be taken with other medications?
Before you start taking TOP AVANA, be sure to tell your doctor about all the medications you are taking . This includes prescription and over-the-counter medications, as well as vitamins and herbal supplements.
There are strict contraindications for the simultaneous use of TOP AVANA with nitrates, nitric oxide donors, MAO inhibitors, thioridazine and potent CYP3A4 inhibitors .
TOP AVANA should be taken with caution from:
- Alpha adrenergic blockers.
- Other drugs for the treatment of ED.
- CYP3A4 inhibitors.
- CYP3A4 inducers.
- Antihypertensive drugs.
- Other SSRIs, SIZON and tricyclic antidepressants.
- Drugs that affect platelet function.
- Warfarin and other anticoagulants.
Who is recommended to buy TOP AVANA in the USA?
TOP AVANA is recommended for purchase in the USA for men aged 18 to 65 who suffer from both erectile dysfunction and premature ejaculation and seek a comprehensive solution to these problems. The drug provides a quick onset of action, a powerful and long-lasting effect, allowing you to regain self-confidence and enjoy a full sexual life.
TOP AVANA is a prescription drug . Before purchasing and taking it, you must consult a doctor . The doctor will conduct an examination, establish a diagnosis, exclude contraindications and select the optimal dosage. It is recommended to buy the drug only in licensed pharmacies to avoid buying counterfeits.
Conclusion
TOP AVANA is an innovative and effective drug for the complex treatment of erectile dysfunction and premature ejaculation in men. The combination of avanafil and dapoxetine provides a rapid onset of action, a stable erection and an increase in the duration of sexual intercourse. However, like any drug, TOP AVANA has its contraindications and can cause side effects. Therefore, before starting to take it, be sure to consult a doctor and strictly follow his recommendations.
Other varieties of this drug: