Why is Tadalafil better than Udenafil (Zydena)?

Erectile dysfunction (ED) is a common condition that affects the quality of life of many men. Fortunately, modern medicine offers effective solutions, among which a special place is occupied by drugs of the phosphodiesterase-5 (PDE-5) inhibitor group. Tadalafil and Udenafil are two prominent representatives of this group that help men regain confidence in their sexual abilities. Both drugs effectively cope with ED, but have certain differences that may affect the choice of a particular patient.

The purpose of this comprehensive text is to provide a detailed analysis and comparison of Tadalafil and Udenafil, revealing their strengths and weaknesses. We will look at their mechanisms of action, pharmacokinetic properties, efficacy, safety profile, and determine when Tadalafil may be the better choice and when Udenafil may be advantageous.

Mechanism of action: common roots and individual nuances

The basis of the action of both Tadalafil and Udenafil is the inhibition of the PDE-5 enzyme. This enzyme plays a key role in regulating blood flow in the penis. In a healthy state, during sexual arousal, nitric oxide (NO) is released in the body, activating the enzyme guanylate cyclase. Guanylate cyclase, in turn, increases the level of cyclic guanosine monophosphate (cGMP). It is cGMP that is responsible for the relaxation of the smooth cavernous muscles of the bodies of the penis, which allows blood to fill them and cause an erection.

PDE5 breaks down cGMP, thereby ending the erection. PDE5 inhibitors, such as Tadalafil and Udenafil, block the action of PDE5, allowing cGMP to build up and maintain an erection longer.

Although both drugs work on the same principle, there are some differences in their selectivity for different PDE subtypes. Tadalafil is known for its high selectivity for PDE5, but also has some affinity for PDE11, which may be associated with some side effects such as back and muscle pain. Udenafil, on the other hand, is considered more selective for PDE5 and has less affinity for other PDE subtypes, which could theoretically reduce the risk of certain side effects.

Pharmacokinetics: time of action and duration of effect

Pharmacokinetics is the science of how the body affects drugs, including absorption, distribution, metabolism, and elimination. The pharmacokinetic properties of Tadalafil and Udenafil differ significantly, which determines their clinical features and affects the patient’s choice.

Tadalafil: Characterized by a long half-life of about 17.5 hours in healthy men. This means that the concentration of the drug in the blood is reduced by half 17.5 hours after administration. Due to this, Tadalafil provides a long-lasting effect – up to 36 hours, and sometimes longer. The onset of action of Tadalafil is usually observed 30-60 minutes after administration. Tadalafil can be taken both as needed, before expected sexual activity, and daily, to ensure constant readiness for sexual intercourse. Food intake does not significantly affect the absorption of Tadalafil.
Udenafil: Has a significantly shorter half-life of about 11-13 hours. This means that its effects last less than Tadalafil, usually up to 24 hours. Udenafil starts to work faster than Tadalafil, usually 15-30 minutes after administration. Udenafil is intended to be taken as needed before sexual activity. The absorption of Udenafil may be somewhat slowed by food, especially fatty foods.

Efficiency: proven results in clinical studies

Both drugs Tadalafil and Udenafil have undergone numerous clinical studies, which have confirmed their effectiveness in the treatment of erectile dysfunction of varying severity and etiology.

Tadalafil: The effectiveness of Tadalafil is well documented. Clinical studies have shown that Tadalafil significantly improves erectile function in men with ED, regardless of age, ethnicity, and underlying medical conditions such as diabetes and hypertension. Tadalafil is effective in a variety of dosage regimens, both as-needed and daily. Daily use of Tadalafil, in particular, has been shown to have a positive effect not only on erectile function but also on the quality of life of men and their partners.
Clinical studies also support Udenafil’s effectiveness in treating ED . Udenafil has shown significant improvements in erectile function compared to placebo. Some studies even point to Udenafil’s potentially faster onset of action compared to other PDE5 inhibitors, which may be an advantage for men who value spontaneity in their sexual relationships. Udenafil’s effectiveness has also been confirmed in men with various comorbidities, including diabetes and cardiovascular disease.

Direct comparative studies of Tadalafil and Udenafil are limited, but the available data suggest that both drugs are effective in treating ED. The choice between them often depends on the patient’s needs, the drugs’ pharmacokinetic characteristics, and side effect profile.

Safety and Side Effects: Weighing the Risks and Benefits

Like all medications, Tadalafil and Udenafil can cause side effects. It is important to understand the potential risks and compare them for both drugs.

Tadalafil: The most common side effects of Tadalafil include headache, facial flushing, nasal congestion, indigestion (upset stomach), back pain, and muscle pain. These side effects are usually mild to moderate and resolve on their own. Less common are more serious side effects such as blurred vision, sudden hearing loss, priapism (prolonged and painful erection). Patients with cardiovascular disease should exercise caution when taking Tadalafil as it may interact with nitrates and other heart medications.
Udenafil: The side effect profile of Udenafil is similar to Tadalafil, but some differences do exist. The most common side effects of Udenafil include headache, flushing, indigestion, dizziness, and palpitations. Back and muscle pain are reported less frequently with Udenafil than with Tadalafil. Like Tadalafil, Udenafil is contraindicated in patients taking nitrates and should be used with caution in patients with cardiovascular disease.

It is important to note that individual responses to medications may vary. Some men may tolerate Tadalafil better, while others may tolerate Udenafil better. Before starting any of these medications, you should consult with your doctor to assess the potential risks and benefits, taking into account your individual health condition and associated medical conditions.

What suits whom: an individual approach to selection

The choice between Tadalafil and Udenafil depends on a man’s individual needs, preferences, and lifestyle. Let’s look at different scenarios and patient profiles to better understand which drug may be more appropriate in each case.

Duration of action is key: If the duration of action of the drug is important to a man, Tadalafil may be the best choice. Its effects can take up to 36 hours, which allows for greater flexibility and spontaneity in sexual relations. This is especially convenient for men who have an active sex life and do not want to plan to take the drug immediately before each sexual act. Taking Tadalafil daily ensures that you are always ready for sexual activity.
Speed of action is an important advantage If a man values a quick onset of action, Udenafil may be a more attractive option. It starts working faster than Tadalafil, which may be important for men who prefer spontaneous sexual intercourse and do not want to wait a long time after taking the pill.
Frequency of sexual activity: For men who have sex less than twice a week, taking Tadalafil or Udenafil as needed may be sufficient. In this case, the choice may depend on other factors, such as the duration of the desired effect and the speed of onset of action. For men with more frequent sexual activity, taking Tadalafil daily may be a more convenient and effective solution.
Side Effect Profile and Individual Tolerance: Although the overall side effect profile of Tadalafil and Udenafil is similar, individual tolerability may vary. Some men may tolerate Tadalafil better, while others may tolerate Udenafil better. If a man has had side effects from one drug in the past, his doctor may recommend trying the other drug. Also, for men prone to back and muscle pain, Udenafil may be a better choice, as these side effects are reported less frequently with it.
Cost of treatment Cost of treatment may also be a factor when choosing between Tadalafil and Udenafil. Prices for the drugs may vary depending on the manufacturer, dosage, and pharmacy chain. Patients should discuss the cost of treatment with their doctor or pharmacist to choose the most cost-effective option.

Tadalafil Benefits: Why It Might Be the Best Choice?

While Udenafil is also an effective drug for treating ED, Tadalafil has a number of benefits that make it a better choice for many men.

Duration of action: The main advantage of Tadalafil is its long half-life and long-lasting effect. 36 hours of action of Tadalafil provide significant flexibility in planning sexual activity and allow a man not to worry about taking a pill immediately before intercourse. This is especially important for couples who value spontaneity and unpredictability of sexual relations.
Daily Dosage Tadalafil is the only PDE5 inhibitor approved for daily use at low doses. Daily use of Tadalafil provides constant readiness for sexual activity at any time without the need to schedule a pill before intercourse. This makes Tadalafil a convenient option for men with regular sexual activity. In addition, daily use of Tadalafil may have additional benefits, such as improving the symptoms of benign prostatic hyperplasia (BPH).
Wide range of dosages and release forms Tadalafil is available in various dosages (2.5 mg, 5 mg, 10 mg, 20 mg) and release forms (film-coated tablets, lozenges). This allows the doctor to individually select the optimal dose and form for each patient, taking into account his needs and individual tolerance.
Additional Benefits for BPH: Tadalafil is approved to treat not only ED, but also the symptoms of BPH. For men who suffer from both conditions, Tadalafil may be especially beneficial because it can treat both problems with one drug.
Large Evidence Base and Experience of Use Tadalafil was first approved for the treatment of ED in 2003 and has a significantly larger clinical experience than Udenafil. The accumulated evidence base for the efficacy and safety of Tadalafil is more extensive and reliable.

The Benefits of Udenafil: When Speed and Tolerability Matter

Udenafil, although inferior to Tadalafil in terms of duration of action, also has its own advantages that may make it a better choice for some men:

Fast onset of action: Udenafil starts working faster than tadalafil, usually within 15 to 30 minutes of taking it. For men who value spontaneity and don’t want to wait a long time after taking a pill, Udenafil may be a more attractive option.
Less Likely to Cause Back and Muscle Pain Some studies suggest that Udenafil may be less likely to cause back and muscle pain than Tadalafil. For men who are prone to these side effects, Udenafil may be a better-tolerated option.
Short duration of action: While many men find Tadalafil’s long-acting nature to be an advantage, some may prefer Udenafil’s shorter duration of action. For example, men who have sex infrequently may prefer a shorter duration of action to avoid the drug’s prolonged effects on the body.
Potentially Lower Cost: In some cases, Udenafil may be slightly cheaper than Tadalafil. For patients for whom cost is an important factor, Udenafil may be a better option.

Conclusion: Individual choice for optimal results

To sum up the comparison of Tadalafil and Udenafil, it is important to emphasize that both drugs are effective and safe for the treatment of erectile dysfunction. The choice between them depends on the individual needs, preferences and lifestyle of the man.

Tadalafil may be a better choice for men who:

They value the long-lasting effect of the drug and spontaneity in sexual relations.
They have a regular sexual life and prefer to take the drug daily.
Suffer from symptoms of BPH in addition to ED.
They are looking for a drug with a large evidence base and extensive experience of use.

Udenafil may be a better choice for men who:

They appreciate the rapid onset of action of the drug.
Are prone to back and muscle pain and want to minimize this risk.
A drug with a shorter duration of action is preferred.
They consider the cost of treatment as the most important factor.

The final decision on choosing between Tadalafil and Udenafil should be made together with a doctor who will be able to assess the individual situation of the patient, take into account all factors and recommend the most appropriate treatment option. Do not self-medicate, contact a specialist for qualified medical care.

Remember that the main goal of ED treatment is to improve the quality of life and restore sexual harmony. Thanks to modern drugs such as Tadalafil and Udenafil, achieving this goal is quite possible.

Why Tadalafil is Better than Udenafil? A Complete Comparison of Erectile Dysfunction Drugs

Erectile dysfunction (ED) is a delicate problem faced by millions of men around the world. It can have a significant impact on quality of life, self-esteem, and relationships. Fortunately, modern medicine offers effective solutions, among which a special place is occupied by drugs of the phosphodiesterase type 5 (PDE5) inhibitor group. Tadalafil and Udenafil are two representatives of this class that have gained popularity due to their ability to improve erectile function. Both drugs help men achieve and maintain an erection necessary for full sexual intercourse. However, despite their common goals, Tadalafil and Udenafil have certain differences that affect their effectiveness, duration of action, side effect profile, and ease of use.

The question of which of these drugs is better is quite natural. Choosing the best ED treatment is an individual process that depends on many factors, including the patient’s needs, health condition, treatment expectations, and readiness for certain side effects. The purpose of this article is to comprehensively compare Tadalafil and Udenafil, reveal their strengths and weaknesses, help understand the nuances of their action, and make an informed choice in favor of one of the drugs. We will consider in detail the mechanisms of action, pharmacokinetic properties, clinical efficacy, safety, and side effect profile of both drugs. Our goal is to provide you with complete and objective information so that you can better understand how Tadalafil differs from Udenafil, and which of them may be more suitable for you.

Mechanism of action: How do Tadalafil and Udenafil work?

To understand the differences between Tadalafil and Udenafil, it is important to understand their combined mechanism of action. Both drugs belong to the group of PDE5 inhibitors. PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP). cGMP, in turn, plays a key role in the erection process. During sexual stimulation, nitric oxide (NO) is released in the cavernous bodies of the penis. NO activates the enzyme guanylate cyclase, which leads to an increase in cGMP levels. Increased cGMP levels cause the smooth muscles of the cavernous bodies to relax and blood to flow to the penis, which ensures an erection.

PDE5, by destroying cGMP, stops the action of the latter, helping to complete the erection. PDE5 inhibitors, such as Tadalafil and Udenafil, block the action of PDE5, preventing the destruction of cGMP. As a result, the level of cGMP remains elevated longer, which contributes to a longer relaxation of smooth muscles and improved blood flow in the penis. It is important to emphasize that the action of PDE5 inhibitors depends on sexual stimulation. The drugs do not cause an erection spontaneously, but only enhance the body’s natural response to sexual arousal.

Although both drugs have a similar mechanism of action, there are some differences in their selectivity for different PDE subtypes. Tadalafil is more selective for PDE5, but can also affect PDE11, which may be associated with some of its side effects, such as back and muscle pain. Udenafil, on the other hand, is considered more selective for PDE5, with less effect on other PDE subtypes. However, the clinical significance of these differences in selectivity is not fully understood and requires further research. Overall, both drugs are effective in inhibiting PDE5, providing improved erectile function, but differences in selectivity may affect their side effect profiles and potential drug interactions.

Pharmacokinetics: duration of action and speed of onset of effect

One of the key differences between Tadalafil and Udenafil is their pharmacokinetics, that is, how the drugs are absorbed, distributed, metabolized, and eliminated from the body. Pharmacokinetic parameters determine the duration of action of the drug, the speed of onset of the effect, and the ease of its use.

Tadalafil has a long half-life of about 17.5 hours. This means that the concentration of the drug in the blood is halved in almost 18 hours. Due to this, Tadalafil has a long-lasting effect – up to 36 hours. The maximum concentration of Tadalafil in the blood plasma is achieved 2 hours after administration. Food intake has virtually no effect on the rate and extent of absorption of Tadalafil. Tadalafil is metabolized in the liver by the enzyme CYP3A4 and is excreted from the body mainly with feces (about 61%) and to a lesser extent with urine (about 36%) in the form of inactive metabolites.

Udenafil , on the contrary, has a shorter half-life – 11-13 hours. The maximum concentration of Udenafil in the blood plasma is achieved faster than that of Tadalafil, 1-1.5 hours after administration. The duration of action of Udenafil is also shorter than that of Tadalafil, and is approximately 24 hours. The pharmacokinetics of Udenafil allows it to be used both once, before the expected sexual activity, and daily. Udenafil is also metabolized in the liver mainly with the participation of the enzyme CYP3A4.

Differences in pharmacokinetics determine different schemes of application and advantages of each drug. The long action of Tadalafil allows it to be taken in advance, even a day before planned sexual activity or daily, ensuring constant readiness for sexual intercourse. The shorter action of Udenafil makes it more suitable for situational use, without the need to plan the intake in advance. The choice between Tadalafil and Udenafil in terms of pharmacokinetics depends on the individual needs and preferences of the patient, the frequency of sexual activity and the desired duration of the drug.

Clinical effectiveness: what does the research say?

The clinical efficacy of Tadalafil and Udenafil in the treatment of erectile dysfunction has been confirmed by numerous studies. Both drugs demonstrated significant improvement in erectile function compared to placebo. Clinical trials assessed the effectiveness of the drugs using various questionnaires, such as the International Index of Erectile Function (IIEF) and the Sexual Encounters Diary (SEP). The results of these studies indicate that both Tadalafil and Udenafil effectively improve the ability to achieve and maintain an erection sufficient for satisfactory sexual intercourse.

One comparative study published in McMaster Optimal Aging found that Udenafil and Tadalafil improved ED symptoms by 33% compared to placebo. However, the risk of side effects was slightly higher for Udenafil (11%) compared to Tadalafil (10%). Other studies also confirm similar efficacy of both drugs. For example, clinical trials of Udenafil at doses of 50 mg and 75 mg taken daily for 12 weeks showed significant improvement in erectile function in patients with ED. Similarly, numerous studies of Tadalafil have confirmed its effectiveness at various doses (from 5 to 20 mg) for both as-needed and daily use.

It is important to note that there are not many direct comparative studies directly comparing the effectiveness of Tadalafil and Udenafil under the same conditions. Most studies have assessed the effectiveness of each drug separately, compared with a placebo. Therefore, based on the available data, it is difficult to draw a clear conclusion about which drug is more effective. Both drugs are effective in treating ED, and the choice between them often depends on other factors, such as individual tolerability, duration of action, and ease of use.

Safety and side effects – what you need to know?

Like any medication, Tadalafil and Udenafil can cause side effects. The side effect profile is the most important factor when choosing a drug for the treatment of ED. In general, PDE5 inhibitors have a similar spectrum of side effects related to their mechanism of action – dilation of blood vessels.

The most common side effects of Tadalafil include headache, flushing of the face (hot flashes), upset stomach, stuffy nose, pain in the muscles, back, arms or legs, nausea and dizziness. In rare cases, more serious side effects may occur, such as priapism (prolonged and painful erection), visual disturbances, sudden hearing loss and cardiovascular complications. It is important to note that serious side effects are rare and most side effects of Tadalafil are mild to moderate and resolve on their own.

Side effects of Udenafil are also similar to other PDE5 inhibitors. The most common are headache, facial flushing, nasal congestion, indigestion, and muscle pain. According to some studies, Udenafil may cause side effects slightly less often than Tadalafil. For example, in the already mentioned McMaster Optimal Aging study, the risk of side effects for Udenafil was slightly higher (11%) than for Tadalafil (10%), but the difference was insignificant. Serious side effects such as priapism, visual and hearing impairment are also possible with Udenafil, although they are rare.

It is important to consider individual tolerance of the drugs. In some patients, Tadalafil may cause fewer side effects, while in others – Udenafil. Also, the side effect profile may depend on the dose of the drug and individual characteristics of the body. Before starting to take any of the drugs, it is important to consult a doctor and discuss possible risks and contraindications.

Contraindications and interactions with other drugs

Tadalafil and Udenafil have similar contraindications and may interact with certain medications. Contraindications for both drugs include:

Concomitant use of nitrates: Nitrates are used to treat angina and other cardiovascular diseases. Concomitant use of PDE5 inhibitors and nitrates can lead to a sharp drop in blood pressure, which is life-threatening.
Severe cardiovascular disease: The use of PDE5 inhibitors is contraindicated in patients with unstable angina, severe heart failure, recent myocardial infarction or stroke.
Severe liver failure: the drugs are metabolized in the liver, so their use is contraindicated in severe liver failure.
Severe renal impairment: In severe renal impairment, the elimination of drugs from the body may be slower, increasing the risk of side effects.
PDE5 inhibitors may affect visual function, so their use is contraindicated in patients with retinitis pigmentosa and other hereditary retinal diseases .
Hypersensitivity to the components of the drug.

Interaction with other drugs Tadalafil and Udenafil may interact with various drugs, including:

Alpha blockers: Concomitant use with alpha blockers used to treat benign prostatic hyperplasia and hypertension may result in a decrease in blood pressure.
CYP3A4 inhibitors: Drugs such as ketoconazole, itraconazole, erythromycin, clarithromycin, ritonavir and others may increase the concentration of Tadalafil and Udenafil in the blood, increasing the risk of side effects.
CYP3A4 inducers: Drugs such as rifampicin, phenytoin, carbamazepine may decrease the concentration of Tadalafil and Udenafil in the blood, reducing their effectiveness.
Other PDE5 inhibitors: Concomitant use with other PDE5 inhibitors is contraindicated due to the increased risk of side effects.
Alcohol: Taking alcohol with Tadalafil or Udenafil may increase some side effects such as dizziness and decreased blood pressure.

Before you start taking Tadalafil or Udenafil, be sure to tell your doctor about all the medications you are taking, including prescription drugs, over-the-counter drugs, vitamins, and herbal supplements. This will help your doctor assess the risk of interactions and choose the best treatment regimen.

For which patients is Tadalafil better suited, and for which is Udenafil better suited?

The choice between Tadalafil and Udenafil depends on the individual needs and preferences of the patient, as well as lifestyle and frequency of sexual activity.

Tadalafil is often called a “weekend drug” because of its long-lasting action. It can be taken in advance, such as on a Friday night, and the effects can be enjoyed over the weekend. This long-lasting action makes Tadalafil convenient for men who are sexually active and do not want to schedule a dose just before intercourse. Daily use of Tadalafil at a low dose (5 mg) is also an option for men who have frequent sexual activity (two or more times a week). Daily use ensures that you are always ready for intercourse and may be more convenient for some patients. Additionally, Tadalafil is also indicated for the treatment of symptoms of benign prostatic hyperplasia (BPH), so for men with a combination of ED and BPH, Tadalafil may be an especially beneficial choice.

Udenafil, with its shorter duration of action, is better suited for situational use. It can be taken immediately before anticipated sexual activity. Udenafil’s rapid onset of action (1-1.5 hours) allows for effects to be achieved fairly quickly after administration. Udenafil may be more convenient for men who have irregular sexual activity or who do not want the drug to last for a long time. For those who prefer to take the drug only when needed, Udenafil may be a better option. Also, some studies suggest a slightly lower risk of side effects with Udenafil, which may be an important factor for patients sensitive to the side effects of medications.

Advantages of Tadalafil over Udenafil

Although both drugs are effective PDE5 inhibitors, Tadalafil has certain advantages over Udenafil that make it a better choice for some men.

Longer action: The main advantage of Tadalafil is its long-lasting action, up to 36 hours. This allows men to be ready for sexual activity for a long time after taking the drug without having to plan the intake immediately before intercourse. Udenafil, with a duration of action of up to 24 hours, requires more precise planning of the time of intake. For men who value spontaneity in sexual relations, Tadalafil may be a more convenient and better choice.
Daily Use Possibility Tadalafil is available in low doses (5 mg), allowing for daily use. Daily use ensures a constant concentration of the drug in the blood and readiness for sexual activity at any time. Udenafil, although it can be used daily, is usually used situationally before sexual intercourse. For men with frequent sexual activity, daily use of Tadalafil may be more convenient and effective.
Treatment of BPH: Tadalafil is the only PDE5 inhibitor approved for the treatment of symptoms of BPH. For men who suffer from both ED and BPH, Tadalafil may be the drug of choice to treat both problems at once. Udenafil is not indicated for the treatment of BPH.
More clinical studies and experience: Tadalafil was approved for the treatment of ED before Udenafil, and therefore has more clinical studies and a longer history of clinical use. This may give doctors and patients more confidence in its effectiveness and safety.

Advantages of Udenafil over Tadalafil

Despite the benefits of Tadalafil, Udenafil also has its own strengths that may make it a better choice for some men:

Faster onset of action: Udenafil starts to act faster than Tadalafil, reaching peak plasma concentrations within 1-1.5 hours of administration, compared to 2 hours for Tadalafil. For men looking for a quicker effect, Udenafil may be a more attractive option.
Possibly slightly lower risk of side effects: Some studies suggest a trend toward a lower risk of side effects with Udenafil compared to Tadalafil, although this difference is not always statistically significant. For patients who are sensitive to side effects or have had negative experiences with other PDE5 inhibitors, Udenafil may be a better choice.
Situational Use Udenafil’s short duration of action makes it ideal for situational use, where the drug is taken only when needed before intercourse. This may be convenient for men with irregular sexual activity who do not want to take the drug constantly or have a long-lasting effect.
Potentially Lower Price: In some regions, Udenafil may be slightly cheaper than Tadalafil, which may be an important factor for patients with limited financial resources.

Conclusion: which drug to choose?

Therefore, Tadalafil and Udenafil are effective and safe drugs for the treatment of erectile dysfunction, belonging to the group of PDE5 inhibitors. Both drugs have a similar mechanism of action and clinical efficacy, but differ in pharmacokinetic properties, duration of action and side effect profile.

Tadalafil benefits from its long-acting, daily dosing, and added benefit of treating BPH symptoms. It is a better choice for men who value spontaneity, have frequent sexual activity, or need treatment for BPH.

Udenafil is attractive due to its faster onset of action, situational use, and potentially lower risk of side effects. It may be a better choice for men with irregular sexual activity or those who prefer to take the drug only when needed.

There is no single answer to the question of which drug is better – Tadalafil or Udenafil. The choice of the optimal drug is individual and depends on the needs, preferences and health of a particular patient. The best solution would be to consult with your doctor. The doctor will be able to assess your individual situation, take into account all factors and help you make an informed choice in favor of Tadalafil or Udenafil, or offer other options for treating erectile dysfunction. Remember that self-medication can be dangerous to your health. Contact a specialist to get qualified help and choose the best treatment that meets your needs.